The Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) is the largest public research organization in Spa in, and it is distinguished by its multidisciplinary nature. Three subgroups are involved in the Kill•Spill project combining expertise in microbial biotechnology, molecular and biochemical analysis of catabolic pathway and the development and application of analytical (meta-) genomic, (meta-) proteomic and (meta-) metabolomic platforms.
Main tasks in the project
- Development and validation of biosensors for alkanes; test their suitability to detect hydrocarbons in seawater (WP2).
- Construction and validation of biosensors for aromatic hydrocarbons (WP2 and WP8)
- Molecular traps for identification of evolved variants of TodS sensor to expand the range of effectors recognized by this sensor regulator (WP2)
- In vitro expression technology for enhanced performance of environmental biosensors (WP2).
- Reprogramming host cells into biochemically components vehicles for in situ monitoring of aromatic hydrocarbons (WP2)
- Analytical (meta-) proteomic and (meta-) metabolomic platforms for assessment bio-stimulation and/or bio-augmentation processes in biodegradation settings.